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Base de datos CISDOC

ID (ISN) del documento27814
Número CIS 77-1616
ISSN - Título de la serie 0340-0131 - International Archives of Occupational and Environmental Health
Año 1977
Número de serie
Autor(es) Triebig G., Schaller K.H., Erzigkeit H., Valentin H.
Título Biochemical and psychological studies in persons with long-term exposure to trichloroethylene with reference to exposure-free intervals
Título original Biochemische Untersuchungen und psychologische Studien an chronisch Trichloräthylen-belasteten Personen unter Berücksichtigung expositionsfreier Intervalle [en alemán]
Información bibliográfica 28 Jan. 1977, Vol.38, No.3, p.149-162. Illus. 21 ref.
Resumen Examination of 8 persons who were occupationally exposed to about 50ppm (260mg/m3) trichloroethylene (the TLV in the Fed.Rep. of Germany) in a printing shop is reported. The purpose of the psychological examinations was to clarify mental function changes correspnding to a "psycho-organic syndrome". In spite of proved incorporation of solvent, no signs of CNS changes were found. Biochemical analysis showed large interindividual variations of trichloroethylene, trichloroethanol and trichloroacetic acid levels in blood and urine and a fall in concentrations after exposure-free intervals. The level of 250mg trichloroethanol and trichloroacetic acid per gram of creatinine, under discussion as an acceptable biological TLV in occupational medicine, was exceeded in all cases. It is proposed to increase it to 300-350mg total metabolites per gram of creatinine. The results are compared with other reports.
Descriptores (primarios) imprenta; tricloroetileno; efectos psicológicos; efectos bioquímicos; disolventes orgánicos
Descriptores (secundarios) Alemania (República Federal de); investigación de higiene del trabajo; vigilancia de la sangre; tests psicológicos; valores umbrales biológicos; metabolitos urinarios
Tipo de documento -
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s)
Navegación por categoria(s) Mental health
Halogenated hydrocarbons
Printing, photography and photocopying industry