ID (ISN) del documento | 26427 |
Número CIS |
77-192 |
ISSN - Título de la serie |
0140-6736 - Lancet |
Año |
1976 |
Número de serie |
|
Autor(es) |
Grady G.F. |
Título |
Relation of e antigen to infectivity of HBsAg-positive inoculations among medical personnel. |
Información bibliográfica |
4 Sep. 1976, Vol.2, No.7984, p.492-494. 12 ref. |
Resumen |
Accidental inoculation of blood containing hepatitis-B surface antigen (HBsAg) resulted in hepatitis B or an anti-HBs response in 60% of cases when e antigen was present, as against 31% when it was not. A soluble protein identified by Magnium and Espmark in sera containing HBsAg, e antigen appears to be a marker of infectivity in maternal-foetal transmission of hepatitis B. The high prevalence of e antigen in patients on renal dialysis units where staff acquired hepatitis B most frequently suggests a comparable association. e antigen was detected in 74% of inocula from chronic renal dialysis and transplantation units, compared with 28% from other services, and the incidence of hepatitis B varied accordingly (22% and 6%, respectively). The validity of linking e antigen with infectivity is briefly discussed. |
Descriptores (primarios) |
antígenos; inmunología; hospitales; hepatitis vírica |
Descriptores (secundarios) |
reacciones serológicas; observación de larga duración |
Tipo de documento |
- |
Tema(s) |
Patología profesional
|
Broad subject area(s) |
|
Navegación por categoria(s) |
Health care services Bacterial and parasitic diseases Viral diseases (other than aids) Liver diseases
|