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Base de datos CISDOC

ID (ISN) del documento26427
Número CIS 77-192
ISSN - Título de la serie 0140-6736 - Lancet
Año 1976
Número de serie
Autor(es) Grady G.F.
Título Relation of e antigen to infectivity of HBsAg-positive inoculations among medical personnel.
Información bibliográfica 4 Sep. 1976, Vol.2, No.7984, p.492-494. 12 ref.
Resumen Accidental inoculation of blood containing hepatitis-B surface antigen (HBsAg) resulted in hepatitis B or an anti-HBs response in 60% of cases when e antigen was present, as against 31% when it was not. A soluble protein identified by Magnium and Espmark in sera containing HBsAg, e antigen appears to be a marker of infectivity in maternal-foetal transmission of hepatitis B. The high prevalence of e antigen in patients on renal dialysis units where staff acquired hepatitis B most frequently suggests a comparable association. e antigen was detected in 74% of inocula from chronic renal dialysis and transplantation units, compared with 28% from other services, and the incidence of hepatitis B varied accordingly (22% and 6%, respectively). The validity of linking e antigen with infectivity is briefly discussed.
Descriptores (primarios) antígenos; inmunología; hospitales; hepatitis vírica
Descriptores (secundarios) reacciones serológicas; observación de larga duración
Tipo de documento -
Tema(s) Patología profesional
Broad subject area(s)
Navegación por categoria(s) Health care services
Bacterial and parasitic diseases
Viral diseases (other than aids)
Liver diseases