| ID (ISN) del documento | 23220 |
| Número CIS |
75-1069 |
| ISSN - Título de la serie |
0041-008X - Toxicology and Applied Pharmacology |
| Año |
1975 |
| Número de serie |
|
| Autor(es) |
Beatty P.W., Lembach K.J., Holscher M.A., Neal R.A. |
| Título |
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on mammalian cells in tissue cultures. |
| Información bibliográfica |
Feb.1975, Vol.131, No.2, p.309-312. 4 ref. |
| Resumen |
A study was made of this substance, a contaminant of the herbicide 2,4,5-trichlorophenoxyacetic acid (2,4,5 T), to ascertain whether its toxic effect in mammals is due to inhibition of mitosis. In contrast with the results using plant endosperm cells, statistical analysis of growth rates and morphological studies using electron microscopy revealed no significant difference in growth patterns and no ultrastructural changes in the control or TCDD-treated cell lines studied. |
| Descriptores (primarios) |
herbicidas; efectos citotóxicos; toxicología; tetraclorodibenzodioxina |
| Descriptores (secundarios) |
ácido triclorofenoxiacético; microscopía electrónica; cultivo de células; pruebas in vitro |
| Tipo de documento |
- |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
|
| Navegación por categoria(s) |
Heterocyclic compounds
Agricultural chemicals
|
