| ID (ISN) del documento | 18739 |
| Número CIS |
73-1378 |
| ISSN - Título de la serie |
0002-8894 - American Industrial Hygiene Association Journal |
| Año |
1972 |
| Número de serie |
|
| Autor(es) |
Griffiths J.E. |
| Título |
Acute inhalation and dermal application screening studies of 2,4,6-trifluoro-sym-triazine and 2,4,6-tris (trifluoromethyl)-sym-triazine |
| Información bibliográfica |
June 1972, Vol.33, No.6, p.382-388. 7 ref. |
| Resumen |
Screening tests for acute inhalation (rats) and dermal toxicity (rabbits) were carried out to evaluate the potential toxicity of 2,4,6-trifluoro-sym-triazine - (FCN)3, commonly known as cyanuric fluoride - and 2,4,6-tris (trifluoromethyl)-sym-triazine - (CF3CN)3 or TTT. The results are presented and discussed. Acute inhalation and acute percutaneous tests with cyanuric fluoride both revealed a high level of toxicity (estimated at LC50=3ppm and LD50=100µL/kg of body weight, respectively). The corresponding values for TTT were LC50=1400ppm and LD50>1000µL/kg. Cyanuric fluoride is particularly insidious: it passes through all layers of the skin and has the property of swelling rubber, so that rubber gloves do not afford adequate protection. Human response, however, cannot be predicted objectively from these tests. |
| Descriptores (primarios) |
compuestos orgánicos fluorados; triacinas; absorción cutánea; inhalación; fluoruro cianúrico |
| Descriptores (secundarios) |
valoración de la toxicidad |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
|
| Navegación por categoria(s) |
Heterocyclic compounds
|
