| ID (ISN) del documento | 112307 |
| Número CIS |
12-0128 |
| ISSN - Título de la serie |
1351-0711 - Occupational and Environmental Medicine |
| Año |
2011 |
| Número de serie |
|
| Autor(es) |
Lee M.S., Magari S., Christiani D.C. |
| Título |
Cardiac autonomic dysfunction from occupational exposure to polycyclic aromatic hydrocarbons |
| Información bibliográfica |
July 2011, Vol.68, No.7, p.474-478. Illus. 40 ref. |
| Acceso Internet |
Cardiac_autonomic_dysfunction_[BUY_THIS_ARTICLE] [en inglés]
|
| Resumen |
Exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with cardiopulmonary mortality and cardiovascular events. This study investigated the association between a biological marker of PAH exposure, assessed by urinary 1-hydroxypyrene (1-OHP), and heart-rate variability in an occupational cohort of boilermakers. Continuous 24 h monitoring of the ambulatory electrocardiogram (ECG) and pre- and postshift urinary 1-OHP were repeated over extended periods of the work week. Data were subjected to statistical analyses. Findings provide evidence that occupational exposure to PAHs is associated with altered cardiac autonomic function. Acute exposure to PAHs may be an important predictor of cardiovascular disease risk in the work environment. |
| Descriptores (primarios) |
hidrocarburos aromáticos; hidrocarburos policíclicos; enfermedades cardiovasculares; valoración de la exposición; calderería; factores de riesgo |
| Descriptores (secundarios) |
hidroxi-1 pireno; dosificación en la orina; electrocardiografía; medida de la frecuencia cardíaca; estudio de cohorte; valoración estadística |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
Patología profesional
Metalurgia, trabajo de los metales
|
| Broad subject area(s) |
Medicina del trabajo, epidemiología
Riesgos químicos
|
| Navegación por categoria(s) |
Aromatic hydrocarbons
Polycyclic hydrocarbons
Cardiovascular diseases
Metalworking industry
|
