| ID (ISN) del documento | 111072 |
| Número CIS |
10-0656 |
| ISSN - Título de la serie |
1351-0711 - Occupational and Environmental Medicine |
| Año |
2010 |
| Número de serie |
|
| Autor(es) |
Jonsson H., Bergdahl I.A., Åkerblom G., Eriksson K., Andersson K., Kågström L., Järvholm B., Damber L. |
| Título |
Lung cancer risk and radon exposure in a cohort of iron ore miners in Malmberget, Sweden |
| Información bibliográfica |
Aug. 2010, Vol.67, No.8, p.519-525. Illus. 19 ref. |
| Resumen |
Lung cancer caused by radon in miners is a well-known risk. However, the risk estimates vary between studies and between mines. This study evaluates the dose response-relationship in a Swedish iron ore mine for which two earlier studies had reached different risk estimates. As this mine has relatively low radon levels, the results are highly relevant for risk estimation in non-uranium underground mines. A new cohort of 5486 male workers employed from 1923 to 1996 was established. Cumulative radon exposures were assessed based on a large number of measurements, including reconstructions of historical conditions. 122 lung cancer cases occurred during the follow-up period of 1958-2000. The average cumulative exposure in underground workers was 32 kBq year/m3h (65 working level months (WLM)), experienced over 14.6 years. The excess RR (ERR) per kBq year/m3h was 0.046. Confounding by quartz may affect these results but appears to account only for 10-20% of the risk. The results for squamous cell and small cell lung cancer were 0.049 and 0.072, respectively. However, no increased risk was observed for adenocarcinoma. The overall risk estimate is about half of that found in the first study for this mine but twice that found in the same cohort in the previously published pooled analysis. Radon did not increase the risk for adenocarcinoma in the lung. |
| Descriptores (primarios) |
radón; sílice; explotación minera en el fondo; cáncer de pulmón; minas de hierro; factores de riesgo |
| Descriptores (secundarios) |
Suecia; valoración del riesgo; valoración de la exposición; factores de confusión; estudio de cohorte; trabajadores masculinos; exposición de larga duración; relación dosis-respuesta |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Sustancias tóxicas y peligrosas
Radiaciones
Minas y canteras
|
| Broad subject area(s) |
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Cancer and carcinogens
Mining and quarrying
Radon
|
