| ID (ISN) del documento | 111016 |
| Número CIS |
10-0554 |
| ISSN - Título de la serie |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Año |
2010 |
| Número de serie |
|
| Autor(es) |
Larson T.C., Antao V.C., Bove F.J. |
| Título |
Vermiculite worker mortality: Estimated effects of occupational exposure to Libby amphibole |
| Información bibliográfica |
May 2010, Vol.52, No.5, p.555-560. 34 ref. |
| Resumen |
The objective of this study was to examine the relationship between cumulative fibre exposure (CFE) and mortality in a cohort of 1862 vermiculite workers exposed to Libby amphibole. Extended Cox regression was used to estimate the hazards associated with CFE as a time-dependent covariate of multiple-cause mortality. The Cox models for mesothelioma, asbestosis, lung cancer, and non-malignant respiratory disease were significant with rate ratios that increased monotonically with CFE. The model for deaths due to cardiovascular disease was also significant. By using a within-cohort comparison, the results demonstrate a clear exposure-response relationship between CFE and mortality from asbestos-related causes. The finding of an association between CFE and cardiovascular mortality suggests persons exposed to Libby amphibole should be monitored for this outcome. |
| Descriptores (primarios) |
Estados Unidos; anfibola; vermiculita; mortalidad; minas |
| Descriptores (secundarios) |
mesotelioma; enfermedades cardiovasculares; enfermedades respiratorias; cáncer de pulmón; asbestosis; estudio de cohorte; valoración estadística |
| Tipo de documento |
D - Artículos periódicos |
| Tema(s) |
Minas y canteras
Patología profesional
Sustancias tóxicas y peligrosas
|
| Broad subject area(s) |
Riesgos químicos
Medicina del trabajo, epidemiología
|
| Navegación por categoria(s) |
Mining and quarrying
|
