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Base de datos CISDOC

ID (ISN) del documento109372
Número CIS 09-396
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2009
Número de serie
Autor(es) Sobus J.R., Waidyanatha S., McClean M.D., Herrick R.F., Smith T.J., Garshick E., Laden F., Hart J.E., Zheng Y., Rappaport S.M.
Título Urinary naphthalene and phenanthrene as biomarkers of occupational exposure to polycyclic aromatic compounds
Información bibliográfica Feb. 2009, Vol.66, No.2, p.99-104. Illus. 25 ref.
Resumen This study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as biomarkers of exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). It involved 39 workers exposed to diesel exhausts (low PAH exposure level), 26 exposed to emissions from asphalt (medium PAH exposure level) and 28 exposed to emissions from coke ovens (high PAH exposure level). Levels of Nap and Phe were measured in urine from each subject. Published levels of airborne Nap, Phe and other PAHs in the relevant sectors were taken into account. Data were subjected to statistical evaluation. It was found that levels of Nap and Phe in urine reflected the workplace atmospheric concentrations of these compounds and therefore constitute promising surrogates for occupational exposures to PAH mixtures.
Descriptores (primarios) motores diesel; fenantreno; hidrocarburos aromáticos; gas de coque; naftaleno; betunes; hidrocarburos policíclicos; tests de exposición; gases de escape
Descriptores (secundarios) espectrometría de masa; fiabilidad; valoración de la exposición; atmósfera respirable; dosificación en la orina; dosificación en el aire; descripción del procedimiento; cromatografía en fase gaseosa; valoración estadística
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaChina; Estados Unidos
Tema(s) Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Biological monitoring
Polycyclic hydrocarbons
Aromatic hydrocarbons