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ID (ISN) del documento109299
Número CIS 09-394
ISSN - Título de la serie 1232-1087 - International Journal of Occupational Medicine and Environmental Health
Año 2007
Número de serie
Autor(es) Szyman£ka-Chabowska A., Antonowicz-Juchniewicz J,, Andrzejak R.
Título The concentration of selected cancer markers (TPA, TPS, CYFRA 21-1, CEA) in workers occupationally exposed to arsenic (As) and some heavy metals (Pb, Cd) during a two-year observation study
Información bibliográfica 3rd quarter 2007, Vol.20, No.3, p.229-239. Illus. 30 ref.
Resumen Molecular epidemiology studies have lately been focused on occupational cancer associated with exposure to chemical carcinogens in the work environment. A two-year observation study was designed to investigate the relationship between arsenic, lead and cadmium concentrations and the levels of cancer markers: TPA (tissue polypeptide antigen), TPS (tissue polypeptide specific antigen), CYFRA 21-1 and CEA (carcinoembryonic antigen) in 69 male workers occupationally exposed to As and Pb, and environmentally exposed to Cd via tobacco smoking. Significant correlations were found between CEA and blood Cd concentrations or between CEA and the duration of work under exposure. All the metals examined were found to have an influence on the concentration of cancer markers, except for CYFRA 21-1. Other findings are discussed.
Descriptores (primarios) cadmio y sus compuestos; substancias cancerígenas; fabricas metalúrgicas; plomo y sus compuestos; arsénico y sus compuestos
Descriptores (secundarios) Polonia; antígenos; dosificación en la orina; observación de larga duración; dosificación en la sangre; valoración de la exposición
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaPolonia
Tema(s) Metalurgia, trabajo de los metales
Sustancias tóxicas y peligrosas
Broad subject area(s) Riesgos químicos
Navegación por categoria(s) Inorganic substances
Arsenic and compounds
Smelting and refining operations
Lead and compounds
Cadmium and compounds