ID (ISN) del documento | 109127 |
Número CIS |
09-37 |
ISSN - Título de la serie |
1076-2752 - Journal of Occupational and Environmental Medicine |
Año |
2008 |
Número de serie |
|
Autor(es) |
Yucesoy B., Kurzius-Spencer M., Johnson V.J., Fluharty K., Kashon M.L., Guerra S., Luster M.I., Burgess J.L. |
Título |
Association of cytokine gene polymorphisms with rate of decline in lung function |
Información bibliográfica |
June 2008, Vol.50, No.6, p.642-648. 37 ref. |
Resumen |
The objective of this study was to investigate whether genetic variants involved in cytokine expression are associated with the age-related rate of decline in one-second forced expiratory volume (FEV1). Gene polymorphisms were investigated in 374 active firefighters for whom the data of at least five pulmonary function tests were available. Findings are discussed. It is concluded that inter-individual variability in progressive decline in FEV1 may be explained in part by genetic variations within genes involved in inflammatory responses. |
Descriptores (primarios) |
lucha contra el fuego; efectos genéticos; función pulmonar |
Descriptores (secundarios) |
Estados Unidos; ADN; sensibilidad individual; pruebas funcionales respiratorias; diferencias por la edad; volumen espiratorio máximo por segundo |
Tipo de documento |
D - Artículos periódicos |
País / Estado o Provincia | Estados Unidos |
Tema(s) |
Patología profesional
|
Broad subject area(s) |
Medicina del trabajo, epidemiología
|
Navegación por categoria(s) |
Antifertility and prenatal effects Incendios Genetic factors in reaction to exposures
|