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Base de datos CISDOC

ID (ISN) del documento108281
Número CIS 08-823
ISSN - Título de la serie 0271-3586 - American Journal of Industrial Medicine
Año 2008
Número de serie
Autor(es) Middleton D.C., Fink J., Kowalski P.J., Lewin M.D., Sinks T.
Título Optimizing BeLPT criteria for beryllium sensitization
Información bibliográfica Mar. 2008, Vol.51, No.3, p.166-172. Illus. 20 ref.
Resumen The beryllium lymphocyte proliferation test (BeLPT) is used to identify persons sensitized to beryllium. An expert panel was convened in 2006 to discuss the BeLPT test, and in particular to propose criteria that would actually establish sensitization. The three criteria proposed by panel members were: one abnormal result; one abnormal and one borderline result; two abnormal results. Complete algorithms were developed for each set of criteria. This study calculated and compared the sensitivity, specificity, and positive predictive values for each set of criteria. Findings are discussed. It is concluded that a single unconfirmed abnormal result is insufficient to establish sensitization for an apparently healthy person. When the prevalence of beryllium sensitization in a group is high, however, even a single abnormal BeLPT can be a strong predictor.
Descriptores (primarios) berilio; sensibilización; fiabilidad; diagnostico
Descriptores (secundarios) linfocitos; descripción del procedimiento; dosificación en la sangre; toma de muestras y análisis
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaEstados Unidos
Tema(s) Patología profesional
Broad subject area(s) Medicina del trabajo, epidemiología
Riesgos químicos
Navegación por categoria(s) Inorganic substances