ILO Home
Volver a la página de entrada
Site map | Contact us English | Français

Base de datos CISDOC

ID (ISN) del documento107902
Número CIS 08-404
ISSN - Título de la serie 1351-0711 - Occupational and Environmental Medicine
Año 2007
Número de serie
Autor(es) Bowler R.M., Roels H.A., Nakagawa S., Drezgic M., Diamond E., Park R., Koller W., Bowler R.P., Mergler D., Bouchard M., Smith D., Gwiazda R., Doty R.L.
Título Dose-effect relationships between manganese exposure and neurological, neuropsychological and pulmonary function in confined space bridge workers
Información bibliográfica Mar. 2007, Vol.64, No.3, p.167-177. Illus. 45 ref.
Resumen This study involved 43 welders exposed to welding fumes containing manganese during the construction of a bridge span, who were administered neurological, neuropsychological, neurophysiological and pulmonary tests. Various outcomes were analysed in relation to blood manganese (MnB) and an estimated cumulative exposure index (CEI). The time weighted average of manganese in air ranged from 0.11-0.46mg/m3. MnB levels of more than 10µg/L were found in 43% of the workers. Lung function values were found to be below normal in 33.3% of the welders. Computer assisted tremor analysis tests, body sway tests and smell identification tests showed impairment in 38.5 to 88% of the welders. Significant inverse dose-effect relationships with CEI and/or MnB were found for IQ, executive function, sustaining concentration and sequencing, verbal learning, working and immediate memory. Dose-effect associations between CEI and sexual function, fatigue, depression and headache reported by the workers were significant. Other findings are discussed.
Descriptores (primarios) efectos neurotóxicos; manganeso y sus compuestos; manganeso; soldadura y corte; humos de soldadura; construcciones y obras publicas; relación dosis-respuesta; Estados Unidos
Descriptores (secundarios) temblores; dosificación en la sangre; apreciación subjetiva; rendimiento cognitivo; trastornos de la sexualidad; jaqueca; neurosis depresiva; trastornos de la memoria; trabajo en espacio confinado; memoria inmediata; fatiga; salud mental; inteligencia; valoración de la exposición; atmósfera respirable; efectos neuropsíquicos; pruebas funcionales respiratorias; dosificación en el aire; tests de las funciones del sistema nervioso
Tipo de documento D - Artículos periódicos
País / Estado o ProvinciaCanadá; Estados Unidos
Tema(s) Construcción e ingenería civil
Metalurgia, trabajo de los metales
Broad subject area(s) Riesgos químicos
Medicina del trabajo, epidemiología
Navegación por categoria(s) Inorganic substances
Diseases of the nervous system
Construction industry and civil engineering
Welding and cutting