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CISDOC database

Document ID (ISN)78737
CIS number 02-677
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2002
Convention or series no.
Author(s) Boojar M.M.A., Goodarzi F.
Title A longitudinal follow-up of pulmonary function and respiratory symptoms in workers exposed to manganese
Bibliographic information Mar. 2002, Vol.44, No.3, p.282-290. 42 ref.
Abstract To study the effects on the respiratory system in mine workers with long-term exposure to manganese (Mn) in the workplace, a follow-up of pulmonary function and respiratory symptoms was carried out among 145 workers employed in a large manganese mine and 65 matched controls. Lung function was measured by recording spirometric parameters. The Mn-exposed workers reported more respiratory symptoms and a significantly higher prevalence of all grades of pulmonary function impairment. All predicted symptoms except for asthma increased significantly in the current smoking group compared with the non-smoking group. There was a significant decrease in FEV1, FVC, and FEV1% values in exposed workers at stages 2 and 3, with an additive effect of the smoking habit. The Mn concentrations in blood, urine, and hair were significantly higher in the exposed workers. The level of cumulative exposure index of workplace Mn was notable and did not change significantly over this study.
Descriptors (primary) manganese; pulmonary function; mining industry; spirometry; respiratory impairment; long-term exposure
Descriptors (secondary) smoking; vital capacity; one-second forced expiratory volume; case-control study; determination in hair; respiratory function tests; determination in blood; determination in urine; confounding factors
Document type D - Periodical articles
Country / State or ProvinceIran, Islamic Republic of
Subject(s) Mines and quarries
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Mining and quarrying
Inorganic substances