Document ID (ISN) | 78663 |
CIS number |
02-575 |
ISBN(s) |
92-4-153041-3 |
Year |
2002 |
Convention or series no. |
CICAD No.41
|
Author(s) |
Inter-Organization Programme for the Sound Management of Chemicals (IOMC) |
Title |
Diethylene glycol dimethyl ether |
Bibliographic information |
World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 2002. iv, 33p. Illus. 107 ref. |
Internet access |
http://www.who.int/ipcs/publications/cicad/en/cicad41.pdf [in English]
|
Abstract |
Conclusions of this criteria document on diethylene glycol dimethyl ether: in vitro studies indicate that the product is not mutagenic nor genotoxic. Animal experiments show no chromosomal aberrations, and indicate low ingestion and inhalation toxicities. The primary form of exposure is by inhalation. Although not conclusive, the limited epidemiological studies involving exposed workers show some indication of reproductive effects (spontaneous abortions among women, lower sperm counts among men). Animal studies confirm the reproductive disorders, and possible mechanisms are discussed. |
Descriptors (primary) |
IPCS; toxicology; diethylene glycol dimethyl ether |
Descriptors (secondary) |
toxic effects; literature survey; antifertility effects; epidemiological aspects; criteria document; UNEP; WHO; ecotoxicology; animal experiments; ILO |
Document type |
B - Chemical safety information sheets |
Country / State or Province | WHO |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Glycol ethers Genetic factors in reaction to exposures
|