| Document ID (ISN) | 78381 |
| CIS number |
02-839 |
| ISSN - Serial title |
0355-3140 - Scandinavian Journal of Work, Environment and Health |
| Year |
2000 |
| Convention or series no. |
|
| Author(s) |
Hjollund N.H.I., Bonde J.P.E., Jensen T.K., Henriksen T.B., Andersson A.M., Kolstad H.A., Ernst E., Giwercman A., Skakkebæk N.E., Olsen J. |
| Title |
Male-mediated spontaneous abortion among spouses of stainless steel welders |
| Bibliographic information |
June 2000, Vol.26, No.3, p.187-192. Illus. 25 ref. |
| Abstract |
Clinical and early subclinical spontaneous abortions were examined among spouses of stainless-steel welders in Denmark. A cohort of men among couples planning a first pregnancy was recruited from members of the union of metal workers and three other trade unions. The cohort was followed for 6 menstrual cycles from the cessation of contraceptive use. Information on pregnancy outcome was collected for all 245 clinically recognized pregnancies. Increased risk of spontaneous abortion was found for pregnancies with paternal exposure to stainless-steel welding (adjusted relative risk 3.5). A mutagenic effect of hexavalent chromium has been found previously in both somatic and germ cells, and the findings could be due to mutations in the male genome. |
| Descriptors (primary) |
antifertility effects; male workers; parental exposure; welding and cutting; abortion; chromium; stainless steel |
| Descriptors (secondary) |
mutagenic effects; embryotoxic effects; expectant mothers; cohort study; long-term study; Denmark |
| Document type |
D - Periodical articles |
| Country / State or Province | Denmark |
| Subject(s) |
Metal production and metalworking
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Welding and cutting
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Diseases of the reproductive system
|
