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CISDOC database

Document ID (ISN)78346
CIS number 02-318
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2001
Convention or series no.
Author(s) Tepper A., Mueller C., Singal M., Sagar K.
Title Blood pressure, left ventricular mass, and lead exposure in battery manufacturing workers
Bibliographic information July 2001, Vol.40, No.1, p.63-72. 31 ref.
Internet access 02-0318.pdf [in English]
Abstract Although debate about the relationship between lead and blood pressure has focused on low environmental lead levels, industrial exposure remains a concern. The blood pressure and left ventricular mass (LVM) in 108 battery manufacturing workers was measured, and the cumulative and historic average measures of blood lead were calculated. It was found that diastolic pressure increased with increasing lead levels, with a significant 5mmHg difference in mean pressure between the highest and lowest cumulative exposure levels. Diastolic pressure increased with the log of cumulative lead. Both hypertension (defined as currently medicated or systolic > 160mmHg or diastolic > 95mmHg) and LVM increased non-significantly with increasing lead exposure. In conclusion, a small effect of blood lead on diastolic blood pressure, particularly for a cumulative measure of exposure was found, but there was no convincing evidence of associations between lead and other blood-pressure-related outcomes.
Descriptors (primary) cardiological effects; arterial blood pressure; storage batteries; lead
Descriptors (secondary) hypertension; determination in blood; long-term exposure
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Cardiovascular diseases
Lead and compounds