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Document ID (ISN)78107
CIS number 02-316
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 2001
Convention or series no.
Author(s) Kelleher P.C., Martyny J.W., Mroz M.M., Maier L.A., Ruttenber A.J., Young D.A., Newman L.S.
Title Beryllium particulate exposure and disease relations in a beryllium machining plant
Bibliographic information Mar. 2001, Vol.43, No.3, p.238-249. Illus. 36 ref.
Internet access 02-0316.pdf [in English]
Abstract The relationship between exposure to beryllium and beryllium sensitization (BeS) and chronic beryllium disease (CBD) was examined in workers in a beryllium machining plant. 20 workers with BeS or CBD (cases) were compared with 206 worker-controls. Cases were more likely to have worked as machinists (odds ratio=4.4) than controls. The median cumulative exposure was 2.9g/m3-years in the cases versus 1.2g/m3-years in controls for total exposure, and 1.7g/m3-years in the cases versus 0.5g/m3-years in the controls for exposure to particles <6m in diameter. Odds ratios were 2.4 for the intermediate exposure group and 1.2 for the high-exposure group compared with the low-exposure group. The median lifetime-weighted (LTW) exposure was 0.25g/m3 in both groups. The median LTW exposure to particles <6m was 0.20g/m3 for cases and 0.14g/m3 for controls. None of the 22 workers with LTW exposure <0.02g/m3 had BeS or CBD. Twelve workers in the case group had LTW exposures >0.20.
Descriptors (primary) beryllium; sensitization; machining; berylliosis
Descriptors (secondary) personal sampling; determination in air; case-control study; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Browse category(ies) Pneumoconioses
Inorganic substances