| Document ID (ISN) | 78107 |
| CIS number |
02-316 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
2001 |
| Convention or series no. |
|
| Author(s) |
Kelleher P.C., Martyny J.W., Mroz M.M., Maier L.A., Ruttenber A.J., Young D.A., Newman L.S. |
| Title |
Beryllium particulate exposure and disease relations in a beryllium machining plant |
| Bibliographic information |
Mar. 2001, Vol.43, No.3, p.238-249. Illus. 36 ref. |
| Abstract |
The relationship between exposure to beryllium and beryllium sensitization (BeS) and chronic beryllium disease (CBD) was examined in workers in a beryllium machining plant. 20 workers with BeS or CBD (cases) were compared with 206 worker-controls. Cases were more likely to have worked as machinists (odds ratio=4.4) than controls. The median cumulative exposure was 2.9µg/m3-years in the cases versus 1.2µg/m3-years in controls for total exposure, and 1.7µg/m3-years in the cases versus 0.5µg/m3-years in the controls for exposure to particles <6µm in diameter. Odds ratios were 2.4 for the intermediate exposure group and 1.2 for the high-exposure group compared with the low-exposure group. The median lifetime-weighted (LTW) exposure was 0.25µg/m3 in both groups. The median LTW exposure to particles <6µm was 0.20µg/m3 for cases and 0.14µg/m3 for controls. None of the 22 workers with LTW exposure <0.02µg/m3 had BeS or CBD. Twelve workers in the case group had LTW exposures >0.20. |
| Descriptors (primary) |
beryllium; sensitization; machining; berylliosis |
| Descriptors (secondary) |
personal sampling; determination in air; case-control study; exposure evaluation |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Metal production and metalworking
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Pneumoconioses
Inorganic substances
|
