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Document ID (ISN)78040
CIS number 02-169
ISSN - Serial title 0003-4878 - Annals of Occupational Hygiene
Year 2000
Convention or series no.
Author(s) Alguacil J., Kauppinen T., Porta M., Partanen T., Malats N., Kogevinas M., Benavides F.G., Obiols J., Bernal F., Rifa J., Carrato A.
Title Risk of pancreatic cancer and occupational exposures in Spain
Bibliographic information Aug. 2000, Vol.44, No.5, p.391-403. 72 ref.
Abstract Cases of pancreatic cancer and controls among hospital patients free of pancreatic cancer were identified during their stay in hospital. Occupational history was obtained by direct interviews with the patients. Occupational exposures to 22 suspected carcinogens associated with pancreatic cancer in previous studies were evaluated. Increased odds ratios (OR) were apparent in all pesticide groups, highest for arsenical pesticides (OR = 3.4) and "other pesticides" (OR = 3.17). ORs were also higher for high-intensity exposure to aniline derivatives, dyes and organic pigments. ORs above 3 were observed for pesticides, benzo(a)pyrene, lead, volatile sulfur compounds, and sedentary work. Results lend support to the hypothesis of an association between exposure to some pesticides and pancreatic cancer. Suggestive increases in risk from aniline derivatives, dyes and organic pigments, and benzo(a)pyrene also deserve further study.
Descriptors (primary) Spain; arsenic; aniline; solvents; dyes; tumour of the pancreas; benzo(a)pyrene; pesticides
Descriptors (secondary) lead; hazard evaluation; exposure evaluation; job-exposure relation; short-term exposure; sulfur and compounds; case-control study
Document type D - Periodical articles
Country / State or ProvinceSpain; Finland
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Endocrine diseases
Agricultural chemicals
Aromatic hydrocarbons
Arsenic and compounds
Aromatic amines
Inorganic substances