| Document ID (ISN) | 77038 |
| CIS number |
01-1131 |
| ISSN - Serial title |
1077-3525 - International Journal of Occupational and Environmental Health |
| Year |
2000 |
| Convention or series no. |
|
| Author(s) |
Hanke J., Dutkiewicz T., Piotrowski J., Baranowska-Dutkiewicz B., Kończalik J. |
| Title |
The absorption of benzene through human skin; Percutaneous absorption studies after forty years |
| Bibliographic information |
Apr.-June 2000, Vol.6, No.2, p.104-113. Illus. 41 ref. |
| Abstract |
This article is an English translation of a Polish study of percutaneous absorption published in 1961. Portions of the original Polish-language article have appeared in many publications, and the article is one of the most commonly cited studies of benzene ever conducted. This research, despite its careful design and the precision of its method, could not be conducted today in most countries of the world. The use of human subjects, including the authors, in a study of skin absorption of a known carcinogen would not be allowed. Some might even object to the publication and citation of the study on ethical grounds. But the importance of this seminal study of the percutaneous absorption of benzene, the interest of the further studies it induced, and its influence over the eventual regulation of benzene exposure in the workplace, is undisputed. The article is followed by a review of percutaneous absorption studies during the last 40 years. |
| Descriptors (primary) |
benzene; organic solvents; skin absorption |
| Descriptors (secondary) |
literature survey; human experiments; determination in urine; translation; description of technique; determination in air |
| Document type |
D - Periodical articles |
| Country / State or Province | Poland |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Ethical issues
Aromatic hydrocarbons
|
