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CISDOC database

Document ID (ISN)76965
CIS number 01-1061
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1999
Convention or series no.
Author(s) Vainio H.
Title Promise of molecular epidemiology - Epidemiological reasoning, biological rationale and risk assessment
Bibliographic information Dec. 1999, Vol.25, No.6, p.498-504. 30 ref.
Abstract Molecular epidemiology has emerged as a natural outgrowth of attempts to apply information derived from the rapid increase in the application of molecular biology to diseases. The incorporation of biomarkers into classical epidemiologic designs holds the promise of unrevealing mechanisms, elucidating gene-environment interactions, and dissecting heterogeneity. The primary interest of molecular epidemiology is in the identification of factors in the physical and social environment which affect the risk for disease and which are amenable to preventive intervention. As experience accumulates, there is new appreciation that attention to study design, infrastructure and biomarker validation can improve the results.
Descriptors (primary) epidemiology; exposure tests; genetic effects; environment
Descriptors (secondary) mutagenic effects; biological and medical tests; exposure evaluation; hazard evaluation
Document type D - Periodical articles
Country / State or ProvinceFrance
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Epidemiology
Biological monitoring