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Document ID (ISN)76783
CIS number 01-667
ISSN - Serial title 1877-7856 - Encyclopédie médico-chirurgicale
Year 1999
Convention or series no. Fascicule 16-048-C-20
Author(s) Benaissa L., Hantson P., Laforge M., Borron S., Baud F.
Title Cyanides and toxic cyanogens
Original title Cyanures et toxiques cyanogéniques [in French]
Bibliographic information Toxicologie-Pathologie professionnelle, 3rd Quarter 1999, No.124, 7p. 59 ref.
Abstract Cyanides are present in many chemicals. Cyanide poisoning is frequent, and found in particular among victims of fires. Cyanide poisoning may lead to headaches, vertigo, agitation, confusion, coma, convulsions and death. Considerable progress has been made in the treatment of cyanide poisoning. A large dose of hydroxocobalamine used in conjunction with oxygen is considered to be the first line of treatment for this type of poisoning, and considerably favours the reanimation process. Symptomatic treatment includes assisted ventilation (breathing of 100% oxygen), correction of acidosis and the maintaining of arterial pressure. The effectiveness of antidote treatment is evaluated initially on the correction of hypotension and lactic acidosis, then on the absence or presence of permanent neurological after-effects.
Descriptors (primary) poisoning; France; antidote treatment; toxicology; cyanides
Descriptors (secondary) acute toxicity; hydroxocobalamine; ingestion; data sheet; smoke; chronic toxicity; encyclopaedia; inhalation
Document type B - Chemical safety information sheets
Country / State or ProvinceFrance
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Inorganic substances