| Document ID (ISN) | 76781 |
| CIS number |
01-666 |
| ISSN - Serial title |
1877-7856 - Encyclopédie médico-chirurgicale |
| Year |
1994 |
| Convention or series no. |
Fascicule 16-002-A-30
|
| Author(s) |
Javelaud B. |
| Title |
Arsenic and its compounds |
| Original title |
Arsenic et dérivés [in French] |
| Bibliographic information |
Toxicologie-Pathologie professionnelle, 4th Quarter 1994, No.105, 7p. 82 ref. |
| Abstract |
Toxicological data sheet on arsenic (As) and its compounds. Metallic arsenic is non-toxic and does not oxidize. The main toxic compounds of As are trivalent, including arsenic trioxide, sodium arsenite and potassium arsenite. The toxicity of pentavelent compounds is less than that of trivalent compounds. Main exposure routes: inhalation, ingestion. Acute toxicity: vomiting, abdominal pain and diarrhoea, followed by cardiovascular symptoms; death from ventricular fibrillation occurs within 10 hours following ingestion; lethal dose is estimated at 1-2mg/kg. Chronic toxicity: effects on the skin; neurotoxic effects; inhalation of arsenical dusts or vapours can give rise to bronchial cancer; liver cancer; cardiovascular effects; haematological effects; effects on the reproductive system. The toxicology of arsine is covered in a specific section. Tables concerning the compensation of occupational diseases caused by arsenic are included. |
| Descriptors (primary) |
occupational diseases; toxicology; arsenic and compounds; France |
| Descriptors (secondary) |
neurotoxic effects; arsenic trioxide; arsenic; sodium arsenite; arsine; ingestion; inhalation; bronchial cancer; liver cancer; lethal dose 50; chromosome changes; haematological effects; chronic toxicity; workmen's compensation; cardiotoxic effects; potassium arsenite; encyclopaedia; data sheet; acute toxicity |
| Document type |
B - Chemical safety information sheets |
| Country / State or Province | France |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Genetic factors in reaction to exposures
Arsenic and compounds
|
