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Document ID (ISN)76656
CIS number 01-827
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 2000
Convention or series no.
Author(s) Pavanello S., Genova A., FoÓ V., Clonfero E.
Title Evaluation of occupational exposure to polycyclic aromatic hydrocarbons by analysis of urinary 1-pyrenol
Original title Valutazione dell'esposizione professionale ad idrocarburi policiclici aromatici mediante l'analisi del livelli urinari de 1-pirenolo [in Italian]
Bibliographic information May-June 2000, Vol.91, No.3, p.192-205. 40 ref.
Abstract Occupational exposure to polycyclic aromatic hydrocarbons (PAH) was assessed by analysing urinary levels of 1-pyrenol. A total of 231 non-smokers exposed to PAH (in industries and occupations including fuel oil power plants, used oil recovery, rubber production, road surface asphalting operations, aluminium anodizing, chimney-sweeping and coke-oven production) were enrolled, together with 53 non-smoker unexposed controls. In the overall population (controls and exposed), multiple linear regression analysis showed that levels of urinary 1-pyrenol were significantly influenced by occupational exposure to PAH in asphalt workers, anodizing plant workers, chimney-sweeps, and coke-oven workers, but not in power plant workers, workers recovering exhausted oils, or rubber production workers. In chimney sweeps and top side coke-oven workers, respectively 2 and 4 subjects exceeded the precautionary level of 1.4Ámoles 1-pyrenol/mole of creatinine; of these, 1 chimney sweep and 3 top side workers exceeded the recommended biological threshold of 2.3Ámoles 1-pyrenol/mole of creatinine.
Descriptors (primary) aromatic hydrocarbons; polycyclic hydrocarbons; determination in urine; exposure tests; 1-hydroxypyrene
Descriptors (secondary) anodizing; threshold limit values; rubber industry; chimney sweeping; creatinine; smoking; thermal power stations; used oils; coke ovens; asphalting; exposure evaluation; case-control study; urinary excretion
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Alcohols
Biological monitoring
Polycyclic hydrocarbons
Aromatic hydrocarbons