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Document ID (ISN)76655
CIS number 01-826
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 2000
Convention or series no.
Author(s) Sartorelli P.
Title Dermal risk assessment in occupational medicine
Original title La stima del rischio cutaneo in medicina del lavoro [in Italian]
Bibliographic information May-June 2000, Vol.91, No.3, p.183-191. 17 ref.
Abstract The importance of the study of dermal exposure to dangerous chemicals has increased during the last few years, mainly because of a reduction of respiratory exposure to toxicants. Pesticides, aromatic amines and polycyclic aromatic hydrocarbons are considered to be the chemicals with the highest dermal risk. In the occupational exposure limit lists of the ACGIH and of many countries, compounds that can be absorbed through the skin are identified by a skin notation, which usually indicates that the percutaneous absorption of the chemical can contribute to the body burden. However, a generally-accepted criterion for assigning skin notation does not exist. It is only when standardized measurements of dermal exposure will be possible that Dermal Occupational Exposure Limits (DOEL) can be set, enabling a regulatory approach in the dermal risk assessment field. So far, attempts to develop health-based DOELs have not been successful, and further work is required to build broad consensus.
Descriptors (primary) skin absorption; exposure tests; permissible levels; toxic substances
Descriptors (secondary) aromatic hydrocarbons; aromatic amines; pesticides; standard; hazard evaluation; skin tests; occupational medicine; polycyclic hydrocarbons
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits
Biological monitoring