ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)76592
CIS number 01-829
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 2001
Convention or series no.
Author(s) Tsuda T., Mino Y., Babazono A., Shigemi J., Otsu T., Yamamoto E.
Title A case-control study of the relationships among silica exposure, gastric cancer, and esophageal cancer
Bibliographic information Jan. 2001, Vol.39, No.1, p.52-57. 24 ref.
Abstract The effect of silica exposure on gastric and oesophageal cancer mortality was investigated in a case-control study restricted to male subjects drawn from death certificates in the Tobi area of Japan. The control group was selected from a series of deaths due to colon cancer, and cancers of other organs. Mantel-Haenszel odds ratios (OR) were estimated after adjustment for age and smoking habits. For gastric cancer, adjusted ORs were 1.22 for brick and quarry work, and 1.36 among silicosis patients. For oesophageal cancer, adjusted ORs were 1.53 for the brick and quarry work, and 2.33 among silicosis patients. The results suggest that gastric and oesophageal cancer were related to silica exposure and silicosis in the study area.
Descriptors (primary) brick and tile industry; oesophageal carcinoma; quarrying industry; mortality; gastrointestinal cancer; silica
Descriptors (secondary) Japan; smoking; occupation disease relation; frequency rates; case-control study; health service records; silicosis
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Gastrointestinal diseases
Mining and quarrying