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Document ID (ISN)76071
CIS number 01-141
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 1999
Convention or series no.
Author(s) Morgan M.S., Schaller K.H.
Title An analysis of criteria for biological limit values developed in Germany and in the United States
Bibliographic information July 1999, Vol.72, No.4, p.195-204. 14 ref.
Abstract The biological tolerance values established by the German Research Foundation and the biological exposure indices developed by the American Conference of Governmental Hygienists represent two extensive lists of occupational exposure guidelines for use in biological monitoring. Although there is substantial agreement between the two organizations on most points, there are several important differences in the approaches taken in the setting of guideline values. Analysis of these distinctions serves to focus attention on the current issues impeding international agreement over occupational exposure guidelines. Among these issues are (1) the specification of the biological monitoring guidelines as ceiling or average values, (2) whether carcinogenic substances should be treated differently from agents with other toxic outcomes, (3) the method of accounting for variability among individual workers, and (4) the extent to which these guidelines should be extended to include genetic markers, indicators of susceptibility, or indicators of early biological response.
Descriptors (primary) USA; biological threshold limits; determination of exposure limits; Germany
Descriptors (secondary) threshold limit values; carcinogens; comment on directive; TLV list; subject variability
Document type D - Periodical articles
Country / State or ProvinceGermany; USA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits