| Document ID (ISN) | 75757 |
| CIS number |
00-1670 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
1999 |
| Convention or series no. |
|
| Author(s) |
Ritz B., Morgenstern H., Froines J., Moncau J. |
| Title |
Chemical exposures of rocket-engine test-stand personnel and cancer mortality in a cohort of aerospace workers |
| Bibliographic information |
Oct. 1999, Vol.41, No.10, p.903-910. 15 ref. |
| Abstract |
A retrospective cohort study of 6,107 aerospace workers was conducted to examine whether exposure to chemicals - primarily hydrazine fuels - during rocket-engine fuelling and testing affects cancer mortality. After adjustment for confounding variables, the estimated rate ratio for lung cancer mortality, comparing exposed to unexposed workers from the same facility, ranged from 1.68 to 2.10, depending on job-duration threshold (6 or 24 months) and lag (0 to 15 years). Similar results were obtained for haematopoietic and lymphopoietic cancer and for bladder and kidney cancer mortality, but estimates for these cancers were imprecise. It is concluded that occupational exposure to hydrazine or other chemicals associated with rocket-engine testing jobs increased the risk of dying from lung cancer, and possibly other cancers, in this population of aerospace workers. |
| Descriptors (primary) |
hydrazines; mortality; aircraft industry; cancer; chemical products |
| Descriptors (secondary) |
leukaemia; renal cancer; frequency rates; lung cancer; cohort study; bladder tumour |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Aerospace manufacturing and maintenance industry
|
