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Document ID (ISN)75554
CIS number 00-1254
ISBN(s) 90-5549-335-x
Year 2000
Convention or series no. Gezondheidsraad Publication 2000/13OSH
Dutch Expert Committee on Occupational Standards (DECOS)
Title Aziridine (ethylene imine) - Health-based calculated occupational cancer risk values
Bibliographic information Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, Sep. 2000. 30p. 11 ref.
Abstract Main topics covered: survey of carcinogenicity studies suitable for risk estimation in the occupational environment; carcinogenic activity in experimental animals under life-time low-dose exposure; health risk to humans; calculation of the health-based conditions; occupational cancer risk values; occupational exposure limits; toxicity profile. The additional lifetime estimated cancer risk for 4,4'-methylenebis(chloroaniline) is estimated to 4 x 10-5 for 40 years of occupational exposure to 0.9µg/m3 and 4 x 10-3 for 40 years of occupational exposure to 90µg/m3. The substance is listed as a carcinogen in several countries (e.g., the Netherlands, Germany, United Kingdom, Sweden, the United States). Of these countries, occupational exposure limits exist in Germany (0.9mg/m3 - TRK) and the United States (0.88mg/m3 - ACGIH). Summary in Dutch.
Descriptors (primary) threshold limit values; carcinogens; toxicology; ethylenimine; Netherlands
Descriptors (secondary) criteria document; toxicity evaluation
Document type B - Chemical safety information sheets
Country / State or ProvinceNetherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits