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Document ID (ISN)75552
CIS number 00-1252
ISBN(s) 90-5549-337-6
Year 2000
Convention or series no. Gezondheidsraad Publication 2000/10OSH
Author(s)
Dutch Expert Committee on Occupational Standards (DECOS)
Title Epichlorohydrin (1-chloro-2,3-epoxypropane) - Health-based calculated occupational cancer risk values
Bibliographic information Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, Sep. 2000. 32p. 15 ref.
Abstract Main topics covered: survey of carcinogenicity studies suitable for risk estimation in the occupational environment; carcinogenic activity in experimental animals under life-time low-dose exposure conditions; health risk in humans; calculation of health-based occupational cancer risk values; occupational exposure limits. The additional lifetime estimated cancer risk for epichlorohydrin is estimated to be 4 x 10-5 for 40 years of occupational exposure to 0.19mg/m3 and 4 x 10-3 for 40 years of occupational exposure to 19mg/m3. The substance is listed as a carcinogen in several countries (e.g., the Netherlands, Germany, the United Kingdom, Sweden, the United States). Occupational exposure limits range from 1.9mg/m3 (Sweden, USA - ACGIH) to 12mg/m3 (Germany). Summary in Dutch.
Descriptors (primary) threshold limit values; carcinogens; epichlorohydrin; toxicology; Netherlands
Descriptors (secondary) criteria document; toxicity evaluation
Document type B - Chemical safety information sheets
Country / State or ProvinceNetherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits
Ethers
Ethylene oxide