|Document ID (ISN)||75552|
|Convention or series no.
||Gezondheidsraad Publication 2000/10OSH
Dutch Expert Committee on Occupational Standards (DECOS)
||Epichlorohydrin (1-chloro-2,3-epoxypropane) - Health-based calculated occupational cancer risk values
||Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, Sep. 2000. 32p. 15 ref.
||Main topics covered: survey of carcinogenicity studies suitable for risk estimation in the occupational environment; carcinogenic activity in experimental animals under life-time low-dose exposure conditions; health risk in humans; calculation of health-based occupational cancer risk values; occupational exposure limits. The additional lifetime estimated cancer risk for epichlorohydrin is estimated to be 4 x 10-5 for 40 years of occupational exposure to 0.19mg/m3 and 4 x 10-3 for 40 years of occupational exposure to 19mg/m3. The substance is listed as a carcinogen in several countries (e.g., the Netherlands, Germany, the United Kingdom, Sweden, the United States). Occupational exposure limits range from 1.9mg/m3 (Sweden, USA - ACGIH) to 12mg/m3 (Germany). Summary in Dutch.
||threshold limit values; carcinogens; epichlorohydrin; toxicology; Netherlands
||criteria document; toxicity evaluation
||B - Chemical safety information sheets
|Country / State or Province||Netherlands|
||Toxic and dangerous substances
|Broad subject area(s)
||Occupational exposure limits