| Document ID (ISN) | 75551 |
| CIS number |
00-1251 |
| ISBN(s) |
90-5549-336-8 |
| Year |
2000 |
| Convention or series no. |
Gezondheidsraad Publication 2000/09OSH
|
| Author(s) |
Dutch Expert Committee on Occupational Standards (DECOS) |
| Title |
4,4'-Methylene bis (2-chloroaniline) - Health-based calculated occupational cancer risk values |
| Bibliographic information |
Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, Sep. 2000. 32p. 16 ref. |
| Abstract |
Main topics covered: survey of carcinogenicity studies suitable for risk estimation in the occupational environment; carcinogenic activity in experimental animals under life-time low-dose exposure; health risk in humans; calculation of health-based conditions; occupational cancer risk values; occupational exposure limits. The additional lifetime estimated cancer risk for 4,4'-methylenebis(chloroaniline) is estimated to be 4 x 10-5 for 40 years of occupational exposure to 0.02mg/m3 and 4 x 10-3 for 40 years of occupational exposure to 2mg/m3. The substance is listed as a carcinogen in several countries (e.g., the Netherlands, Germany, Sweden, the United States). Occupational exposure limits range from 0.005mg/m3 (United Kingdom) to 0.11mg/m3 (USA - ACGIH). Summary in Dutch. |
| Descriptors (primary) |
threshold limit values; carcinogens; toxicology; methylenebis(2-chloroaniline); Netherlands |
| Descriptors (secondary) |
criteria document; toxicity evaluation |
| Document type |
B - Chemical safety information sheets |
| Country / State or Province | Netherlands |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Occupational exposure limits
|
