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Document ID (ISN)75551
CIS number 00-1251
ISBN(s) 90-5549-336-8
Year 2000
Convention or series no. Gezondheidsraad Publication 2000/09OSH
Author(s)
Dutch Expert Committee on Occupational Standards (DECOS)
Title 4,4'-Methylene bis (2-chloroaniline) - Health-based calculated occupational cancer risk values
Bibliographic information Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, Sep. 2000. 32p. 16 ref.
Abstract Main topics covered: survey of carcinogenicity studies suitable for risk estimation in the occupational environment; carcinogenic activity in experimental animals under life-time low-dose exposure; health risk in humans; calculation of health-based conditions; occupational cancer risk values; occupational exposure limits. The additional lifetime estimated cancer risk for 4,4'-methylenebis(chloroaniline) is estimated to be 4 x 10-5 for 40 years of occupational exposure to 0.02mg/m3 and 4 x 10-3 for 40 years of occupational exposure to 2mg/m3. The substance is listed as a carcinogen in several countries (e.g., the Netherlands, Germany, Sweden, the United States). Occupational exposure limits range from 0.005mg/m3 (United Kingdom) to 0.11mg/m3 (USA - ACGIH). Summary in Dutch.
Descriptors (primary) threshold limit values; carcinogens; toxicology; methylenebis(2-chloroaniline); Netherlands
Descriptors (secondary) criteria document; toxicity evaluation
Document type B - Chemical safety information sheets
Country / State or ProvinceNetherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits