| Document ID (ISN) | 75441 |
| CIS number |
00-1382 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
1996 |
| Convention or series no. |
|
| Author(s) |
Kreiss K., Zhen B. |
| Title |
Risk of silicosis in a Colorado mining community |
| Bibliographic information |
Nov. 1996, Vol.30, No.5, p.529-539. Illus. 17 ref. |
| Abstract |
The exposure-response relationship for silicosis was investigated among 134 men over age 40 who had been identified in a previous community-based random sample study in a mining town. Thirty-two per cent of the 100 dust-exposed subjects had radiologic profusions of small opacities of 1/0 or greater at a mean time since first silica exposure of 36.1 years. Of miners with cumulative silica exposures of 2mg/m3-years or less, 20% had silicosis; of miners accumulating > mg/m m3-years, 63% had silicosis. Logistic regression models demonstrated that time since last silica exposure and either cumulative silica exposure or a combination of average silica exposure and duration of exposure predicted silicosis risk. Exposure-response relations were substantially higher using measured silica exposures than using estimated silica exposures based on measured dust exposures assuming a constant silica proportion of dust, consistent with lower levels of exposure misclassification. |
| Descriptors (primary) |
silica; mining industry; hazard evaluation; silicosis |
| Descriptors (secondary) |
USA; Colorado; respirable dust; opacities; dose-response relationship; statistical evaluation; chest radiography; long-term exposure |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Dust, aerosols and related diseases
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Mining and quarrying
Risk evaluation
Pneumoconioses
|
