|Document ID (ISN)||75309|
|Convention or series no.
||Gezondheidsraad publication 1999/12OSH
Dutch Expert Committee on Occupational Standards (DECOS)
||N-Nitrosodimethylamine (NDMA) - Health-based calculated occupational cancer risk values
||Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, 1999. 33p. 19 ref.
||Additional lifetime cancer risk for dimethylnitrosoamine amounts to 4 x 10-5 for 40 years of occupational exposure to 0.002µg/m3, and 4 x 10-3 for 40 years of occupational exposure to 0.2µg/m3. Main topics covered: carcinogenicity studies and selection of the study suitable for risk estimation in occupational situations; carcinogenic activity in experimental animals, life-time low-dose exposure; health risk to humans; health risk to workers, calculation of the health-based calculated occupational cancer risk values; existing occupational exposure limits; toxicity profile (highly toxic, hepatotoxicity, centrilobular necrosis with haemorrage, followed by ascites and jaundice). Summary in Dutch.
||threshold limit values; carcinogens; toxicology; dimethylnitrosoamine; Netherlands
||toxicity evaluation; criteria document; carcinogenic effects
||B - Chemical safety information sheets
|Country / State or Province||Netherlands|
||Toxic and dangerous substances
|Broad subject area(s)
||Occupational exposure limits