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Document ID (ISN)75309
CIS number 00-1088
ISBN(s) 90-5549-298-1
Year 1999
Convention or series no. Gezondheidsraad publication 1999/12OSH
Dutch Expert Committee on Occupational Standards (DECOS)
Title N-Nitrosodimethylamine (NDMA) - Health-based calculated occupational cancer risk values
Bibliographic information Gezondheidsraad, Postbus 16052, 2500 BB Den Haag, Netherlands, 1999. 33p. 19 ref.
Abstract Additional lifetime cancer risk for dimethylnitrosoamine amounts to 4 x 10-5 for 40 years of occupational exposure to 0.002µg/m3, and 4 x 10-3 for 40 years of occupational exposure to 0.2µg/m3. Main topics covered: carcinogenicity studies and selection of the study suitable for risk estimation in occupational situations; carcinogenic activity in experimental animals, life-time low-dose exposure; health risk to humans; health risk to workers, calculation of the health-based calculated occupational cancer risk values; existing occupational exposure limits; toxicity profile (highly toxic, hepatotoxicity, centrilobular necrosis with haemorrage, followed by ascites and jaundice). Summary in Dutch.
Descriptors (primary) threshold limit values; carcinogens; toxicology; dimethylnitrosoamine; Netherlands
Descriptors (secondary) toxicity evaluation; criteria document; carcinogenic effects
Document type B - Chemical safety information sheets
Country / State or ProvinceNetherlands
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Occupational exposure limits