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Document ID (ISN)75081
CIS number 00-716
ISSN - Serial title 0002-8894 - American Industrial Hygiene Association Journal
Year 1999
Convention or series no.
Author(s) Esmen N.A., Hall T.A., Stone R.A., Marsh G.M., Gula M.J., Gause C.K.
Title An investigation of secondary exposure misclassification effects of lifelong occupational history in exposure estimation
Bibliographic information Mar.-Apr. 1999, Vol.60, No.2, p.175-181. Illus. 16 ref.
Abstract In most studies, only the direct effects of misclassification of the interpretation of results of occupational epidemiological studies are considered, or - alternatively - simple estimates of misclassification rates are assigned to various types of exposure estimation processes. Lifelong job profile data obtained from a previously published case-control study provided job histories of 511 decedents. An analysis of these work histories and the comparison of exposures related to longest-held job to estimated total lifetime exposures suggest that single job-based exposure estimates may lead to significant exposure misclassification rates. In addition, the appearance of shorter duration jobs in a study population occurring predominantly early in the work history may exacerbate problems associated with exposure misclassification. The inclusion of extensive recording of the work history of study subjects emerges as a reasonable basis for the investigation and potential reduction of secondary misclassification of exposures in occupational epidemiological studies.
Descriptors (primary) epidemiology; history; exposure evaluation
Descriptors (secondary) conditions of exposure; length of service; epidemiologic study; statistical evaluation; length of exposure; job-exposure relation; exposure records; confounding factors
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Exposure evaluation
Epidemiology