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Document ID (ISN)74993
CIS number 00-727
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Rapiti E., Sperati A., Miceli M., Forastiere F., Di Lallo D., Cavariani F., Goldsmith D.F., Perucci C.A.
Title End stage renal disease among ceramic workers exposed to silica
Bibliographic information Aug. 1999, Vol.56, No.8, p.559-561. 28 ref.
Abstract To evaluate whether ceramic workers exposed to silica experience an excess of end stage renal disease, a cohort of 2,980 male ceramic workers was enrolled during the period 1974-91 in Civitacastellana, Lazio, Italy. For each worker, employment history, smoking data and X-ray film readings were available. Vital status was ascertained for all cohort members. All 2,820 people still alive and resident in the Lazio region as of June 1994 were searched for a match in the regional end stage renal diseases registry, which records all patients undergoing dialysis treatment in public and private facilities of the region. A total of 6 cases was detected when 1.87 were expected. The excess risk was present among non-smokers and smokers, as well as among workers without silicosis and workers with silicoses. The risk was higher among subjects with <20 years since first employment than among those employed >20 years. These results provide further evidence that exposure to silica dust among ceramic workers is associated with nephrotoxic effects.
Descriptors (primary) silica; pottery industry; renal diseases; morbidity
Descriptors (secondary) Italy; quartz; smoking; silicosis; radiography; long-term exposure; health service records; statistical evaluation; cohort study
Document type D - Periodical articles
Country / State or ProvinceItaly; USA
Subject(s) Occupational pathology
Broad subject area(s) Industries and occupations
Browse category(ies) Glass, pottery and related materials
Diseases of the kidney and the urinary system