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CISDOC database
| Document ID (ISN) | 74901 |
| CIS number |
00-709 |
| ISSN - Serial title |
1351-0711 - Occupational and Environmental Medicine |
| Year |
2000 |
| Convention or series no. |
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| Author(s) |
Elliott P., Arnold R., Cockings S., Eaton N., Järup L., Jones J., Quinn M., Rosato M., Thornton I., Toledano M., Tristan E., Wakefield J. |
| Title |
Risk of mortality, cancer incidence, and stroke in a population potentially exposed to cadmium |
| Bibliographic information |
Feb. 2000, Vol.57, No.2, p.94-97. 22 ref. |
| Abstract |
The English village of Shipham has very high concentrations of cadmium in the soil. A previous cohort study of residents from 1939 to 1979 showed overall mortality below that expected, but a 40% excess of mortality from stroke. This study extends the follow up of the cohort to 1997. Standardized mortality and incidence ratios were estimated with regional reference rates. Comparisons were made with the nearby village of Hutton. All-cause mortality was lower than expected in both villages, although there was excess cancer incidence in both Shipham and Hutton. There was an excess of mortality from hypertension, cerebrovascular disease, and nephritis and nephrosis, of borderline significance, in Shipham. In a geographical study, all-cause mortality in Shipham was also lower than expected. There was an excess in genitourinary cancers in both Shipham and Hutton. In conclusion, no clear evidence of health effects from possible exposure to cadmium in Shipham was found despite the extremely high concentrations of cadmium in the soil. |
| Descriptors (primary) |
cerebral embolism; cadmium; cancer; mortality |
| Descriptors (secondary) |
hypertension; United Kingdom; nephritis; frequency rates; cohort study; long-term study; nephrosis |
| Document type |
D - Periodical articles |
| Country / State or Province | United Kingdom |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
Occupational medicine, epidemiology
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| Browse category(ies) |
Inorganic substances
Diseases of the nervous system
Cadmium and compounds
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