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Document ID (ISN)74353
CIS number 00-148
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Koh D., Seow A., Ong C.N.
Title Applications of new technology in molecular epidemiology and their relevance to occupational medicine
Bibliographic information Nov. 1999, Vol.56, No.11, p.725-729. 49 ref.
Abstract Technical advances in molecular biology are described which, combined with epidemiological methods, can shed light on understanding the biological processes associated with disease development. As end users, OEM practitioners should consider the impact of these advances on their practices. The availability of genetic tests to identify susceptible workers raises issues of ethics, individual privacy, right to work, and the relevance of such tests. Several studies have presented data on the association of environmental measurements and various biomarkers for internal and biologically effective dose, genetic polymorphisms, and early response markers. Given the limitations of individual molecular biomarkers in assessing risk to health, and the multifactorial nature of environmental disease, such an approach will increase understanding of the complex issue of mechanisms of disease and further refine the process of risk assessment.
Descriptors (primary) epidemiology; occupational medicine; new technologies
Descriptors (secondary) DNA; chemoreceptors; ethics; genetic screening; exposure tests; immunology
Document type D - Periodical articles
Country / State or ProvinceSingapore
Subject(s) Medicine, hygiene and first aid
Broad subject area(s) New technologies
Browse category(ies) Epidemiology