| Document ID (ISN) | 73585 |
| CIS number |
99-1567 |
| ISSN - Serial title |
0003-4878 - Annals of Occupational Hygiene |
| Year |
1997 |
| Convention or series no. |
|
| Author(s) |
McDonald J.C., McDonald A.D. |
| Title |
Chrysotile, tremolite and carcinogenicity |
| Bibliographic information |
Dec. 1997, Vol.41, No.6, p.699-705. 18 ref. |
| Abstract |
An analysis was made of deaths from mesothelioma, and cancers of the lung, larynx, stomach, colon and rectum in a cohort of some 11,000 Quebec chrysotile workers. Risks were estimated for work in the central mine area and in mines located peripherally. Tremolite concentration was some four times higher in the former area than in the latter. There was increased risk of mesothelioma and lung cancer associated with work in the central mine area, but no increased risk for gastric, intestinal or laryngeal cancer. In the peripheral mines, there was little or no evidence of increased risk for any of these cancers. The hypothesis that, because of the difference in distribution of fibrous tremolite, cancer risk in the central area would be greater than in the periphery was thus substantiated. Topics: amphibole; asbestos mining; asbestos; cancer; carcinogenic effects; chrysotile; tremolite; cohort study; gastrointestinal cancer; hazard evaluation; laryngeal cancer; lung cancer; mesothelioma; mineral fibres; pleural mesothelioma; Quebec. |
| Descriptors (primary) |
asbestos; chrysotile; asbestos mining; tremolite; cancer; amphibole |
| Descriptors (secondary) |
mesothelioma; Quebec; laryngeal cancer; pleural mesothelioma; carcinogenic effects; mineral fibres; gastrointestinal cancer; hazard evaluation; cohort study; lung cancer |
| Document type |
D - Periodical articles |
| Country / State or Province | United Kingdom |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Asbestos
Mining and quarrying
|
