| Document ID (ISN) | 73399 |
| CIS number |
99-1241 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
1999 |
| Convention or series no. |
|
| Author(s) |
Milby T.H., Baselt R.C. |
| Title |
Hydrogen sulfide poisoning: Clarification of some controversial issues |
| Bibliographic information |
Feb. 1999, Vol.35, No.2, p.192-195. 34 ref. |
| Abstract |
Data on the toxicity of hydrogen sulfide are reviewed. It is concluded that: certain neurotoxic effects of exposure are probably due to a direct toxic effect on the brain, while others are almost certainly a result of hypoxia secondary to H2S-induced respiratory insufficiency; pulmonary oedema is a common consequence of poisoning and there is suggestive evidence of hyperactive airway responses in some individuals following brief H2S-induced unconsciousness (knockdown); criteria for acceptable community levels are very different than those governing occupational standards; urinary thiosulfate determinations can be useful for monitoring occupational exposure; and determination of sulfide ion concentrations in blood or major organs can be useful in corroborating a diagnosis of fatal H2S toxicity, but there are many pit-falls in collecting, storing, and analyzing tissue and fluid samples. Topics: acute poisoning; hydrogen sulfide; determination in blood; determination in urine; exposure tests; hypoxia; limitation of exposure; lung diseases; neurotoxic effects; pulmonary function; pulmonary oedema; thiosulfates; urine monitoring. |
| Descriptors (primary) |
neurotoxic effects; lung diseases; hydrogen sulfide; acute poisoning |
| Descriptors (secondary) |
thiosulfates; hypoxia; limitation of exposure; pulmonary function; pulmonary oedema; exposure tests; urine monitoring; determination in urine; determination in blood |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Diseases of the respiratory system (except for pneumoconiosis & similar)
Diseases of the nervous system
Inorganic sulfur compounds
|
