Document ID (ISN) | 73356 |
CIS number |
99-1254 |
ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
Year |
1999 |
Convention or series no. |
|
Author(s) |
Straif K., Weiland S., Werner B., Wienke A., Keil U. |
Title |
Elevated mortality from nonalcohol-related chronic liver disease among female rubber workers: Is it associated with exposure to nitrosamines? |
Bibliographic information |
Mar. 1999, Vol.35, No.3, p.264-271. Illus. 54 ref. |
Abstract |
In a long-term mortality study of 2,875 female rubber workers in a plant producing tires or technical rubber goods, the excess mortality from cirrhosis of the liver was most pronounced for nonalcohol-related cirrhosis of the liver. Mortality from alcohol-related cirrhosis of the liver and from other alcohol-related diseases was not significantly elevated. All cases of nonalcohol-related cirrhosis had worked in production of technical rubber goods and risks increased with earlier years of hire and with longer duration of employment in this work area. Although results should be interpreted with caution, they suggest that the observed excess deaths from cirrhosis of the liver are associated with occupational risk factors. Exposure to nitrosamines may be a plausible risk factor. Topics: alcoholism; cirrhosis; cohort study; dose-response relationship; exposure evaluation; hepatic diseases; mortality; nitroso amines; risk factors; rubber industry; women. |
Descriptors (primary) |
rubber industry; nitroso amines; women; hepatic diseases; mortality |
Descriptors (secondary) |
alcoholism; cirrhosis; dose-response relationship; cohort study; risk factors; exposure evaluation |
Document type |
D - Periodical articles |
Country / State or Province | Germany |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Liver diseases Rubber industry Alcohol and drug abuse
|