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Document ID (ISN)73351
CIS number 99-1177
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Rees D., Myers J.E., Goodman K., Fourie E., Blignaut C., Chapman R., Bachmann M.O.
Title Case-control study of mesothelioma in South Africa
Bibliographic information Mar. 1999, Vol.35, No.3, p.213-222. 27 ref.
Abstract In a study of mesothelioma and asbestos exposure in South Africa, data on cases and controls were collected from referral hospitals and exposure information was collected by interview. None of the 123 cases studied had purely chrysotile exposure. 23 cases had mined cape crocidolite, three had mined amosite, and three had mined Transvaal crocidolite plus amosite. A minimum of 22 cases had exclusively environmental exposure, 20 being from the NW Cape crocidolite mining area. The relative risks associated with environmental exposure in the NW Cape (crocidolite) were larger than for environmental exposure in the NE Transvaal (amosite and crocidolite). Results confirm the importance of environmental exposure in the Cape crocidolite mining area, the relative paucity of cases linked to amosite, and the rarity of chrysotile cases. They are consistent with a fibre gradient in mesotheliomagenic potential for South African asbestos, with crocidolite > amosite > chrysotile. Topics: asbestos mining; asbestos; crocidolite; chrysotile; amosite; case-control study; exposure evaluation; geographical variables; mesothelioma; neighbourhood populations; questionnaire survey; South Africa.
Descriptors (primary) mesothelioma; South Africa; asbestos mining; neighbourhood populations; asbestos
Descriptors (secondary) amosite; chrysotile; crocidolite; geographical variables; questionnaire survey; case-control study; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceSouth Africa
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Asbestos
Mining and quarrying