|Document ID (ISN)||73344|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Bos P.M.J., Brouwer D.H., Stevenson H., Boogaard P.J., de Kort W.L.A.M., van Hemmen J.J.
||Proposal for the assessment of quantitative dermal exposure limits in occupational environments: Part 1. Development of a concept to derive a quantitative dermal occupational exposure limit
||July-Dec. 1998, Vol.55, No.12, p.795-804. Illus. 48 ref.
||An attempt was made to develop a quantitative dermal occupational exposure limit (DOEL) complementary to respiratory occupational exposure limits (OELs). The DOEL refers to the total dose deposited on the skin during a working shift. Based on available data and experience a theoretical procedure for the assessment of a DOEL was developed. A DOEL was derived for cyclophosphamide and 4,4'-methylene dianiline (MDA) according to this procedure. The DOEL for MDA was tested for applicability in an occupational exposure scenario. The proposed concept for a DOEL is relevant and can be made applicable for health surveillance in occupational situations where dermal exposure contributes notably to systematic exposure. For Part 2, see CIS 99-1236. Topics: methylenedianiline; description of technique; determination of exposure limits; exposure tests; limitation of exposure; skin absorption; threshold limit values.
||methylenedianiline; determination of exposure limits; skin absorption
||threshold limit values; description of technique; exposure tests; limitation of exposure
||D - Periodical articles
|Country / State or Province||Netherlands|
||Toxic and dangerous substances
|Broad subject area(s)