|Document ID (ISN)||70197|
|ISSN - Serial title
||0019-8366 - Industrial Health
|Convention or series no.
||Bogadi-Šare A., et al.
||Genotoxic effects in workers exposed to benzene: With special reference to exposure markers and confounding factors
||July 1997, Vol.35, No.3, p.367-373. 31 ref.
||Cytogenetic tests were carried out on the lymphocytes of 49 female shoemakers exposed to benzene and toluene. Levels of benzene and toluene in the workers' blood and levels of phenol in urine were also measured. Chromosome aberration analysis revealed a significant increase in dicentric incidence in the exposed workers with respect to a control group. While significant correlation between cytogenetic test results and exposure biomarkers was not established, correlation between cytogenetic test results and data on confounding factors (age, alcohol consumption) was marked. The influence of confounding factors should be considered when estimating individual genotoxicity risk related to low level benzene exposure.
||benzene; toluene; shoemakers; genetic effects; exposure tests; organic solvents
||confounding factors; determination in urine; analysis of chromosome aberrations; determination in blood
||D - Periodical articles
|Country / State or Province||Croatia|
|Broad subject area(s)
||Antifertility and prenatal effects
Footwear, leather and fur industry
Genetic factors in reaction to exposures