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CISDOC database

Document ID (ISN)68663
CIS number 97-577
ISSN - Serial title 0095-6562 - Aviation, Space, and Environmental Medicine
Year 1996
Convention or series no.
Author(s) Rahill A.A., Weiss B., Morrow P.E., Frampton M.W., Cox C., Gibb R., Gelein R., Speers D., Utell M.J.
Title Human performance during exposure to toluene
Bibliographic information July 1996, Vol.67, No.7, p.640-647. 20 ref.
Abstract Six adults were exposed to either conditioned room air or 100ppm toluene for 6h, including 30min of exercise. Physiological and neuropsychological assessments were carried out. Following exercise, the mean blood and exhaled air toluene levels averaged 1.5µg and 28ppm respectively; lung function was unchanged post-exposure. Both the brief neuropsychological tests and the prolonged multitask performance tests detected an effect of toluene. Differences in performance between air and toluene conditions were greatest after exercise, indicating that physical activity may enhance the response to volatile organic solvents.
Descriptors (primary) neurotoxic effects; toluene; pulmonary function; organic solvents; mental work capacity
Descriptors (secondary) human experiments; perceptual-motor performance
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational physiology
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic hydrocarbons
Mental workload
Diseases of the nervous system