| Document ID (ISN) | 68417 |
| CIS number |
97-172 |
| ISSN - Serial title |
0960-3271 - Human and Experimental Toxicology |
| Year |
1996 |
| Convention or series no. |
|
| Author(s) |
Granath F., Rohlén O., Göransson C., Hansson L., Magnusson A.L., Törnqvist M. |
| Title |
Relationship between dose in vivo of ethylene oxide and exposure to ethene studied in exposed workers |
| Bibliographic information |
1996, Vol.15, p.826-833. Illus. 29 ref. |
| Abstract |
In vivo doses of ethylene oxide (EO) arising from ethylene exposure in plastics industry workers were estimated through haemoglobin adducts, determined in samples collected on one occasion in exposed groups. Exposure doses were estimated by using data from the hygienic surveillance programme. The results of this and of a second study with repeated blood sampling in a few persons show a metabolic conversion of ethylene to ethylene oxide of only 0.5%, which is unexpectedly low. The cancer risk associated with ethylene exposure was also estimated. The estimated risk of cancer due to this level of life-long exposure to ethene is 1 x 10-5 per year. |
| Descriptors (primary) |
carcinogens; personal sampling; metabolic process; haemoglobin monitoring; ethylene oxide; plastics industry; exposure tests; ethylene |
| Descriptors (secondary) |
Sweden |
| Document type |
D - Periodical articles |
| Country / State or Province | Sweden |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Chemical industry
Plastics industry
Biological monitoring
Ethers
Aliphatic and alicyclic hydrocarbons
Ethylene oxide
|
