| Document ID (ISN) | 68092 |
| CIS number |
96-2094 |
| ISSN - Serial title |
0355-3140 - Scandinavian Journal of Work, Environment and Health |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Suarez-Almazor M.E., Soskolne C.L., Fung K., Jhangri G.S. |
| Title |
Empirical assessment of the effect of different summary worklife exposure measures on the estimation of risk in case-referent studies of occupational cancer |
| Bibliographic information |
Aug. 1992, Vol.18, No.4, p.233-241. 25 ref. |
| Abstract |
The effect of different summary worklife exposure measures (i.e. measurements attributing weightings to either duration or concentration of exposure or both) on the estimation of risk in case-referent studies of occupational cancer was analyzed by comparing two matched case-referent studies (from southern Ontario, Canada, and Baton Rouge, Louisiana, USA) associating exposure to sulfuric acid with cancer. Five summary exposure measures were converted to discrete exposure levels through the use of sophisticated statistical methods. The Ontario data set exhibited only minor differences across the 5 exposure measures. The Louisiana data set, however, produced different results, and the time-dependent measures appeared to underestimate the risk. It is possible, therefore, to obtain different estimates of risk from different exposure measures. It is recommended that, in the absence of proved models for assessing exposure, a variety of summary measures be used to estimate risk. This approach would facilitate the comparison of findings across studies. |
| Descriptors (primary) |
epidemiology; length of exposure; exposure evaluation |
| Descriptors (secondary) |
Canada; Ontario; USA; Louisiana; comparative analysis; case-control study; sulfuric acid; mathematical analysis; mathematical models; cancer |
| Document type |
D - Periodical articles |
| Country / State or Province | Canada |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Exposure evaluation
Epidemiology
|
