ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)67589
CIS number 96-1777
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 1996
Convention or series no.
Author(s) Solomon G.M., Morse E.P., Garbo M.J., Milton D.K.
Title Stillbirth after occupational exposure to N-methyl-2-pyrrolidone - A case report and review of the literature
Bibliographic information July 1996, Vol.38, No.7, p.705-713. 58 ref.
Abstract A case report is presented of a pregnant laboratory technician who suffered intrauterine growth retardation and stillbirth following exposure to N-methyl-2-pyrrolidone. Animal studies have demonstrated that this solvent is embryotoxic after maternal exposure to doses that have minimal or no adverse effect on the mother. Laboratory work and solvent exposure have both been previously associated with adverse reproductive outcomes. Laboratory health policies should allow for voluntary removal of prospective parents in situations of possible exposure.
Descriptors (primary) embryotoxic effects; laboratory work; methylpyrrolidinone; expectant mothers; organic solvents
Descriptors (secondary) literature survey; eczema; case study
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Heterocyclic compounds