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CISDOC database
| Document ID (ISN) | 67428 |
| CIS number |
96-1739 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
1996 |
| Convention or series no. |
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| Author(s) |
Wilt J.L., Banks D.E., Weissman D.N., Parker J.E., Vallyathan V., Castranova V., Dedhia H.V., Stulken E., Ma J.K.H., Ma J.Y.C., Cruzzavala J., Shumaker J., Childress C.P., Lapp N.L. |
| Title |
Reduction of lung dust burden in pneumoconiosis by whole-lung lavage |
| Bibliographic information |
June 1996, Vol.38, No.6, p.619-624. Illus. 35 ref. |
| Abstract |
While no effective therapy exists to prevent the progression of pneumoconioses, whole-lung lavage (WLL) might limit the rate of disease progression through the removal of dust, inflammatory cells and cytokines. WLL was performed on two miners who both demonstrated normal lung function and chest radiographs showing ILO profusion category 2 nodular interstitial changes. Relatively large quantities of non-coal mineral dust and cells were recovered along with proinflammatory cytokines, growth factors and cellular enzymes. Long-term clinical trials are necessary to establish the value of this treatment in the management of dust-induced pulmonary disease. |
| Descriptors (primary) |
mineral dust; bronchopulmonary lavage; pneumoconiosis; lung deposition |
| Descriptors (secondary) |
coalworkers pneumoconiosis |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Dust, aerosols and related diseases
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| Broad subject area(s) |
Chemical safety
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| Browse category(ies) |
Pneumoconioses
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