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CISDOC database

Document ID (ISN)66749
CIS number 96-864
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1993
Convention or series no.
Author(s) Seixas N.S., Robins T.G., Attfield M.D., Moulton L.H.
Title Longitudinal and cross sectional analyses of exposure to coal mine dust and pulmonary function in new miners
Bibliographic information Oct. 1993, Vol.50, No.10, p.929-937. 30 ref.
Internet access 96-0864.pdf [in English]
Abstract The association between exposure to dust and pulmonary function was studied by longitudinal and cross-section analyses in a group of US underground coal miners beginning work in or after 1970. The cohort included 977 miners examined both in round two (R2)(1972-75) and round four (R4)(1985-88) of the National Study of Coal Workers' Pneumoconiosis. The results indicated a rapid initial (at R2) loss of FVC and FEV1 in association with cumulative exposure of the order of 30mL per mg/m3-years. After some 15 years since first exposure (at R4), a statistically significant association of cumulative exposure with FEV1 of about -5.9mL per mg/m3-years was found. These results indicate a significant non-linear effect of exposure to dust on pulmonary function at dust concentrations present after regulations took effect. The initial responses in both the FVC and FEV1 are consistent with inflammation of the small airways in response to exposure to dust.
Descriptors (primary) coal dust; functional respiratory disorders; coal mining; respiratory function tests; respirable dust
Descriptors (secondary) pulmonary function; ventilatory capacity; exposure evaluation; comparative study; long-term study; air sampling; cross-sectional study
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Mines and quarries
Broad subject area(s) Chemical safety
Browse category(ies) Mining and quarrying
Diseases of the respiratory system (except for pneumoconiosis & similar)