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CISDOC database

Document ID (ISN)66186
CIS number 96-274
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1995
Convention or series no.
Author(s) Karačić V., Skender L., Bosner-Cucančić B., Bogadi-Sare A.
Title Possible genotoxicity in low level benzene exposure
Bibliographic information Mar. 1995, Vol.27, No.3, p.379-388. 30 ref.
Abstract Structural chromosome aberrations and sister chromatid exchanges (SCEs) in peripheral blood were studied in female workers in the shoe-making industry in Croatia in 1987 and 1992. Occupational exposure to benzene and toluene were determined. Levels of atmospheric benzene and benzene absorption were higher in 1987 (a period of intensified production) than in 1992 (reduced production), but still lower than permissible levels. There was an increase in dicentric chromosomes in both groups compared to a non-exposed control group; higher SCE frequencies were observed in the 1987 group. Genotoxicity may occur in workers exposed to low levels of benzene.
Descriptors (primary) benzene; shoe industry; genetic effects; toluene
Descriptors (secondary) phenol; chromosome changes; determination in urine; determination in blood; determination in air
Document type D - Periodical articles
Country / State or ProvinceCroatia
Subject(s) Medicine, hygiene and first aid
Broad subject area(s) Chemical safety
Browse category(ies) Footwear, leather and fur industry
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Aromatic hydrocarbons