|Document ID (ISN)||65703|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Mikoczy Z., SchŘtz A., Hagmar L.
||Cancer incidence and mortality among Swedish leather tanners
||Aug. 1994, Vol.51, No.8, p.530-535. 30 ref.
||Cancer incidence and mortality patterns were assessed for the periods 1958-89 and 1952-89 respectively, in a cohort of 2,026 subjects who had been employed for at least one year between 1900 and 1989 in three Swedish leather tanneries. Cause-specific standardized incidence and mortality ratios (SIRs and SMRs) were calculated. A significantly increased incidence of soft tissue sarcomas (SIR 4.27; 95% CI 1.39-9.97) was found, based on five cases. An excess (not statistically significant) was also found for multiple myelomas and sinonasal cancer. The increased incidence of soft tissue sarcomas adds support to previous findings of an excess mortality in this diagnosis among leather tanners. A plausible cause is exposure to chlorophenols, which had occurred in all three plants. The excess of multiple myelomas may also be associated with exposure to chlorophenol. The association between incidence of cancer and specific chemical exposure should be elucidated in a cohort-based case-referent study.
||carcinogens; Sweden; tanning industry; cancer; mortality
||sarcomas; nasal cancer; myeloma; leather and fur industries; chlorophenols; long-term study; cohort study
||D - Periodical articles
|Country / State or Province||Sweden|
||Leather, fur and footwear
|Broad subject area(s)
||Occupational medicine, epidemiology
||Footwear, leather and fur industry