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Document ID (ISN)65703
CIS number 95-2075
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1994
Convention or series no.
Author(s) Mikoczy Z., SchŘtz A., Hagmar L.
Title Cancer incidence and mortality among Swedish leather tanners
Bibliographic information Aug. 1994, Vol.51, No.8, p.530-535. 30 ref.
Abstract Cancer incidence and mortality patterns were assessed for the periods 1958-89 and 1952-89 respectively, in a cohort of 2,026 subjects who had been employed for at least one year between 1900 and 1989 in three Swedish leather tanneries. Cause-specific standardized incidence and mortality ratios (SIRs and SMRs) were calculated. A significantly increased incidence of soft tissue sarcomas (SIR 4.27; 95% CI 1.39-9.97) was found, based on five cases. An excess (not statistically significant) was also found for multiple myelomas and sinonasal cancer. The increased incidence of soft tissue sarcomas adds support to previous findings of an excess mortality in this diagnosis among leather tanners. A plausible cause is exposure to chlorophenols, which had occurred in all three plants. The excess of multiple myelomas may also be associated with exposure to chlorophenol. The association between incidence of cancer and specific chemical exposure should be elucidated in a cohort-based case-referent study.
Descriptors (primary) carcinogens; Sweden; tanning industry; cancer; mortality
Descriptors (secondary) sarcomas; nasal cancer; myeloma; leather and fur industries; chlorophenols; long-term study; cohort study
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Leather, fur and footwear
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Footwear, leather and fur industry